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published evidence that BPH is caused by failure in the spermatic venous drainage system resulting in increased hydrostatic pressure and local testosterone levels elevated more than 100-fold above serum levels
Ruotolo G, Howard BV
Curr Opin Oncol 2007;19:249
Studies of both mice and humans show the anti-inflammatory effects (such as reductions in TNF-) occur within hours, suggesting some actions are independent of weight loss or long-term metabolic change
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