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Studies have shown that reducing the content of FMO3 in insulin-resistant mice can inhibit FoxO1 (the central node of metabolic control), reduce the production of TMAO, and completely prevent the development of hyperglycemia, hyperlipidemia, and atherosclerosis (84)
doi: 10.1056/NEJMoa1509225 98 HernandezAFGreenJBJanmohamedSDAgostinoRBSr.GrangerCBJonesNPet al
Glucagon-like peptide-1 analogues - an efficient therapeutic option for the severe insulin resistance of lipodystrophic syndromes: two case reports
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