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Clinical studies examining oxidative stress biomarkers in individuals with migraine have found that the number of monthly headache days was negatively correlated with serum concentrations of two antioxidant enzymes, catalase and superoxide dismutase, and total antioxidant capacity while being positively correlated with serum levels of glutathione peroxidase 1, nitric oxide, and malondialdehyde (3739)

There is a higher chance of damage in digestion, which can cause bloating, or nausea, particularly at high doses

doi:10.1016/j.urolonc.2008.10.019 (2009)

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