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Likewise, a 2010 phase III, randomized, double-blind, placebo-controlled, parallel-group study undertaken in Europe found that MT1 reduced the severity of PLE when administered as a 16 mg implant over a four-month period [14]
Moreover, this work highlights new mechanistic targets for chronotherapeutic strategies aimed at mitigating inflammation in metabolic disease
Side effects are minimal and typically include mild soreness at the injection site
The raw metabolomic data have been deposited in the MetaboLights database under accession numbers MTBLS12367, MTBLS12370, and MTBLS12371 for public access
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