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RCT (Frye et al., 2016) A 12-week double-blind trial evaluated high-dose leucovorin in children with ASD and language delay [1]

10.1042/bj3200345 25 EatonS.FukumotoK.StefanuttiG.SpitzL.ZammitV

The improvement may reflect easing drug shortages, expanded insurance coverage and better management of side effects

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