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While there is some existing research on berberine as a standalone supplement, the evidence doesn't support the idea that it works as effectively as a prescription GLP-1 medication , and studies on the transdermal delivery method (absorbing supplements through the skin) for these ingredients are lacking
Reddy, N
Metformin and exenatide upregulate hepatocyte nuclear factor-4, sex hormone binding globulin levels and improve hepatic triglyceride deposition in polycystic ovary syndrome with insulin resistance rats
In the body, thioctic acid activates a protein that binds to glutathione and works as an antioxidant
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