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Common current practice in other research laboratories is to store the reconstituted working stock at 2 to 8C, protected from light, and use it within roughly 28 to 30 days
Thus, gene therapy with viral vectors protects from neuronal death in animal models of ALS (Lee et al., 2019) and cerebral ischemia (Hayashi et al., 2001), promotes angiogenesis, and reduces apoptosis in SCI (Kitamura et al., 2007)
The authors described TB4 as acting through promotion of cell migration, stem cell mobilisation and differentiation, and inhibition of inflammation and apoptosis