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Phenethyl Isothiocyanate Protects against High Fat/Cholesterol Diet-Induced Obesity and Atherosclerosis in C57BL/6 Mice

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As a non-invasive administration pathway, oral mucosal delivery effectively bypasses gastrointestinal digestion and hepatic first-pass metabolism, significantly elevating systemic bioavailability and reducing drug metabolism loss compared with conventional oral dosage forms

Regulatory bodies like the European Medicines Agency (EMA) are actively facilitating the approval of new GLP-1 therapies, which is expected to drive market expansion