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HoffmannLa Roche, Basel, Switzerland)
51 Sayin SI, Wahlstrm A, Felin J, Jntti S, Marschall HU, Bamberg K, Angelin B, Hytylinen T, Orei M, Bckhed F
Methods Animals and housing Male Sprague-Dawley rats ( Rattus norvegicus ) weighing 225-250g were obtained from Taconic Laboratories (Rensselaer, NY)
GHK-Cus gene modulation capacity was documented in a landmark microarray analysis by Pickart et al., identifying 4,000+ gene targets including VEGF upregulation (angiogenesis), SOD2 upregulation (oxidative defense), and downregulation of pro-inflammatory cytokine genes including TNF- and IL-6
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