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A note on the research itself: the mechanisms the brand describes - NAD+'s role in cellular energy production, growth hormone's role in tissue repair, and B-vitamin methylation pathways - are active areas of general biomedical research
More long-term study is needed
Rapid weight loss can be associated with reductions in bone mineral density, which is of particular relevance to perimenopausal and postmenopausal women who are already at increased risk of osteoporosis
Insulin resistance is very common in older people and usually leads to type 2 diabetes
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