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The STEP 5 trial confirmed that at 2 years, weight loss stabilized at -15.2% from baseline meaning the body reaches a new set point where caloric intake and expenditure balance out (Garvey et al., 2022)
These representations are not easily translated to what the average participant looked like or their health risks at the outset of the study and how improvements in adiposity and clinical measures changed with treatment
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Research suggests that the peptide may influence cellular activity related to telomeres , telomerase , and the bodys natural repair mechanisms
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