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Fig.3 Proportion of patients achieving MASH resolution without worsening of fibrosis with tirzepatide [6] While GLP-1 RAs are proving effective in treating MASH, their lack of direct action on liver tissue could limit their effectiveness in patients with advanced liver fibrosis or cirrhosis
Despite the link, the role of insulin abnormalities in PD remains contentious, with little difference found between patients with PD and healthy controls in peripheral insulin resistance, quantified using a hyperinsulinemic-euglycemic clamp [71]
10.1002/edm2.70132 91 MocciaroG.CapodiciA.De AmicisR
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