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Gastrointestinal disorders Less frequent: Gastrointestinal complaints, such as nausea, vomiting, diarrhoea and abdominal pain
This tends to be more severe in the legs and is characterized by axonal degeneration without demyelinization
Because it acts through the same receptor as ghrelin, experimental models have repeatedly shown links to changes in hunger signaling, energy intake, and neuroendocrine responses to food
Furthermore, researchers have shown that glutamine antagonists can inhibit cancer cell oxidative and glycolytic metabolism, thereby reducing tumor hypoxia, acidosis, and nutrient consumption
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