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There is no direct dose equivalence because the receptor profiles differ, but 8 mg Retatrutide is a reasonable starting point for comparable efficacy with slightly better tolerability than the 12 mg maximum
References M.A
Better Safe than Sorry The truth is, even if you aren't prone to side effects and even if you aren't worried about slightly decreased bioavailability, it's still best to follow the best practices as recommended by the manufacturer of semaglutide
M.MartinezF
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