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10.1007/BF00404074 Diabetologia 58 HammermanM
As mentioned above, GSH cellular concentrations are regulated by GSH-mediated GCL inhibition (Figures 2, 3)
A larger randomized, placebo-controlled intervention trial (the SELECT study) in more than 35,000 middle-aged and selenium-replete men, randomized to receive selenium (in the form of selenomethionine, 200 g/day) and/or vitamin E supplementation, was halted because of concerns regarding an increased risk of type 2 diabetes mellitus with selenium and increased risk of prostate cancer with vitamin E (84, 85)
Rather than protecting the peptide through the stomach, this formulation aims for sublingual and buccal absorption
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