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doi: 10.1038/s41572-020-0184-y 3 BrandtFThvilumMHegedsLBrixTH

Addressing these challenges will provide clearer insights into the role of probiotics in managing NAFLD ( Figure 1 )

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Since a complex microbiota was found to be necessary for worsening -synuclein pathology, it is likely that a combination of the increase in harmful bacteria, decrease in beneficial bacteria, and similar changes in their derived products trigger and facilitate -synuclein fibril formation, propagation, and disease pathology (Figure 2)