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When mitochondria fail, the body cannot generate enough energy to meet even basic metabolic demands, directly causing the severe physical exhaustion and post-exertional malaise (PEM) that leaves patients bedbound after minor exertion

You will need to talk to your insurance company to see if either of these medications will be covered

Other reactions warranting urgent GP contact include: Unexplained muscle weakness or cramping Persistent vomiting or severe abdominal pain Signs of hypokalaemia (low potassium) during initial treatmentmuscle weakness, irregular heartbeat, or severe fatigue In patients with severe, longstanding B12 deficiency, rapid correction can occasionally precipitate hypokalaemia as new red blood cells are produced, consuming available potassium

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