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GIPRs have been localized to human pancreatic -cells, and intravenous GIP infusion activates GIPR and intracellular signaling in pancreatic -cells, augmenting glucagonotropic effects in hypoglycemic conditions in humans (130)
Adv Sci
Second, SNPs significantly associated with GLP1R gene expression in blood were identified, applying a p-value threshold of 5 10 and a minor allele frequency criterion of 1%
Vitamin B-12 deficiency, in particular, can result in peripheral neuropathy and megaloblastic anemia, both of which have significant health implications
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