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Although the majority of first-time prescriptions occurred in the 45-64 age group, a higher proportion of patients with off-label prescriptions were female (off-label: 69%, on-label: 61%) and between 18-25 (off-label: 30%, on-label: 22%)
Importantly, sweating can be a sign of hypoglycemia, especially in patients taking tirzepatide with insulin or sulfonylureas
In addition, more lipophilic drugs will tend to pass not only through the BBB, but also to other organs, which consequently results in a reduced availability of drugs to enter the brain (27)
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