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After 24 weeks, the active drug group lost between 7.2% and 17.5% of their body weight (depending on dose), compared to a 1.6% loss in the placebo group
The ongoing clinical trial should provide clearer evidence
GLP-1RAs attenuate systemic and local inflammation by inhibiting the p38 MAPK/NF-B pathway, reducing cytokine production, endothelial injury, and microvascular thrombosis
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