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SURMOUNT-4 demonstrated that continued treatment is necessary to maintain weight lossdiscontinuation results in gradual weight regain
The increased PEP also inhibited phosphofructose kinase (encoding by pfk ) activity, which was responsible for the decreased glycolytic flux and the down regulation of the glycolytic activities [33]
The gap in life expectancy from preventable physical illness in psychiatric patients in Western Australia: retrospective analysis of population based registers
Nat Rev Cancer 2006
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