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Description

PGC-1alpha is an inducible transcriptional co-activator whose muscle expression is massively increased by endurance exercise, cold exposure (in BAT), and prolonged fasting (in liver) three physiological contexts characterized by increased oxidative energy demand

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10.1038/s41593-019-0540-y 93 KastenhuberE

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Glucagon is demonstrated to increase energy expenditure

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