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Its important to rotate the injection site, choosing between the abdomen, thigh, or upper arm, with each dose to prevent irritation

Studies consistently show that weight regain begins soon after stopping medication and is proportional to the amount of weight originally lost: Semaglutide (Wegovy) : In the STEP 1 extension study, participants who lost an average of 17% of their body weight regained approximately two-thirds of that weight within one year of stopping the medication

In the Phase 2 trial (Jastreboff et al., NEJM 2023), the lowest randomized maintenance dose arm was 1mg per week

In terms of skin benefits, it reduces melanin production, which may result in a brighter and more even complexion over time