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doi: 10.1186/1471-2288-14-43 14 Garcia-FloresVRomeroRMillerDXuYDoneBVeerapaneniCet al
But a person on semaglutide is experiencing GLP-1 receptor activation at levels that dwarf anything your body naturally produces, because synthetic GLP-1 receptor agonists are designed to be resistant to the DPP-4 enzyme that rapidly degrades natural GLP-1
Mechanism: Understanding why it happens could lead to prevention strategies or adjunct treatments that allow higher doses without dysesthesia
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