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A single ascending dose, first-in-human phase 1 study to assess the safety and pharmacokinetic profile of LY3437943 was performed on 47 healthy participants (ClinicalTrials.gov, NCT03841630)
Cruciferous vegetables are dual-acting: They provide some dietary glutathione directly AND activate Nrf2-mediated upregulation of glutathione synthesis genes via sulforaphane [27][28]
Severe GI side effects that prevent you from maintaining adequate hydration despite your best efforts
It also has FDA approval
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