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This literature review was conducted following the PICO Framework, with details available in Supplementary material 1

Among the tested formulations, PNP-1-10-0.05 Sema-1.8 mg/mL exhibited the most favorable safety profile across all evaluated tissues, while PNP-1-10-0.05 TZP-4.5 mg/mL, though eliciting a modest increase in localized tissue response, remained substantially more biocompatible than daily bolus TZP

The SingleCare prices in this article are the most accurate at the time of publishing in ZIP code 23666 as of May

Those with a familial or personal history of medullary thyroid cancer or certain endocrine conditions should avoid this treatment