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And although these medications may sometimes seem like the closest thing we have to a magic pill, they still work best alongside nutritious eating, physical activity, adequate sleep, and other healthy habits

Finally, is important to highlight that physiological brain insulin sensitivity has also been identified as a predictor of successful weight loss (220)

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In a phase 3 trial (OASIS 4) comparing oral semaglutide 25 mg (the Wegovy pill) to placebo, the most common side effects were: Nausea Vomiting Constipation Indigestion (dyspepsia) Diarrhea Most side effects were mild or moderate and went away without stopping treatment