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In follicular macrophages from RA, upregulation of the BCAA transporter SLC7A5 is closely associated with activation of the mTORC1 signaling pathway, which in turn promotes M1 macrophage polarization and arthritic tissue damage (87)
Front Nutr 9:853058 Fgc LN, Carneiro BA, Alves GS, Lins Silva DH, Faria Guimaraes D, Souza LS, Bandeira ID, Beanes G, Miranda Scippa A, Quarantini LC (2022) Metabolomics of major depressive disorder: a systematic review of clinical studies
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