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CRISPR-Cas9 whole genome-wide gene-knockout screens for suppressors and enhancers of C9orf72 DPRs in human cells revealed TMX2 as an important protective modifier against toxicity (Kramer et al., 2018)
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doi:10.1002/jor.21107
However, when your small intestines produce large amounts of hydrogen gas, food starts to move too quickly through the digestive system and causes loose stools
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