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But if you are optimizing for comfort, after dinner with a 2 to 3 hour bedtime buffer is the sweet spot most users find works best

In the 1960s, manufacturers introduced short-term weight-loss medications such as phentermine, benzphetamine, and diethylpropion, but researchers did not collect long-term safety data (8)

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But for shedding pounds, the results show the average body weight reduction of about 10% continued for a year and was more or less sustained for up to four years