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The current approved dose of exenatide is 5 or 10 g given twice-daily

(3) This theorized pathway involves the activation of phospholipase C (PLC), which some researchers believe may lead to the increased release of inositol triphosphate (IP3) and diacylglycerol (DAG)

Pelo (Protein pelota homolog) forms a complex with GTPase Hbs1 (Hsp70 subfamily B suppressor1) to rescue the stalled ribosomes in the terminal step of protein synthesis, and thus Pelo-Hbs1 complex is a well-known surveillance factor in ribosome-associated quality control machinery 16,17

Moreover, stimulation of GLP-1R in BMSCs results in the accumulation of -catenin in the cell nucleus