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It avoids turning pathway relevance into a broad product claim
+ - Given its potentially adverse effects, ranging from disruption of the insulin system to cancer, the exogenous augmentation of IGF-I is not an attractive or effective method of increasing muscle mass or function
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Metabolism and disposition of intravenously administered acetyl-L-carnitine in healthy volunteers Eur J Clin Pharmacol 1989
It happens when the body is under physiological stress like rapid weight loss, inflammation, hormonal shifts, or nutritional deficiency
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