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SIBO Small intestinal bacterial overgrowth (SIBO), in particular methane dominant SIBO, sometimes called intestinal methanogen overgrowth (IMO), contributes to constipation by interfering with normal digestion and gut motility
Standard dosing is 2.4mg weekly via subcutaneous injection, titrated slowly over 12-16 weeks
In the central nervous system, GLP-1R signaling within hypothalamic circuits increases satiety and reduces food intake, ultimately promoting body weight reduction
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