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This is usually a gradual, subtle shift rather than a dramatic change
Necroptosis plays a dual role in tumour immune regulation, as it can activate antigen-specific immune responses by releasing damage-associated molecular patterns, while RIPK3/MLKL-mediated IL-1 release can suppress T-cell function and promote tumour immune escape [59]
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Notably, probiotics have shown considerable promise in reducing the incidence of certain cancers, especially colorectal and bladder cancer (296, 297)
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