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Conversely, GGCT overexpression elevated TCA cycle intermediates (Fig
On the other hand, SGLT-2is influence glucose sensing or absorption in specific neurons, and suppresses the sympathetic nervous system, thus regulating the cardiovascular activity, lowering energy expenditure, and maintaining glucose homeostasis in the pancreas and kidney (Figure 2)
We studied VPA toxicokinetics using a nonlinear mixed-effects model-based population approach and modeled individual plasma VPA/blood lactate concentration relationships
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