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NAC has been tried in numerous chronic diseases with similarly disappointing results, including cystic fibrosis protection against contrast-induced nephropathy and thrombosis [14]

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The glutathione cycle shapes synaptic glutamate activity

The same set of experiments was conducted for GSSSG-pretreated HGF as a control and results indicated a nearly negligible preventive-effect on HGF nitration (Figure 2c), consistent with the earlier observation that GSSSG treatment barely enhanced HGF-c-met interaction before and after exposure to peroxynitrite (see again Figure 1e, bars 47 and bars 47 )