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They fall instead under the general remit of the Human Medicines Regulations 2012, which is why unlicensed injectable preparations cannot lawfully be supplied for human administration regardless of "research use only" labelling [3][4]

There is also a physiological reason to expect the gastric arm to be self-limiting

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For B12 to be absorbed properly, it must bind with a protein called "intrinsic factor," which is produced in the stomach