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Regardless of what broader uses may be on the horizon, hospitals and health systems will need to evaluate how these medications change patient risk factors and current treatments and provide wrap-around services for patients who use these medications.

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Obese patients, have been reported to produce more SCFAs in their intestines (310), but indeed meaningful diet-induced shifts in SCFA production fluxes have proven not sufficient to modulate peripheral levels of GLP-1 and PYY (311)

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These medications are not available for cosmetic weight loss or for individuals seeking to reduce belly fat alone without meeting clinical thresholds

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