retatrutide fda approval 2026 is getting a lot of attention, and for good reason. Early data looks promising, but it's still in clinical trials and not FDA-approved The numbers from Lilly's Phase

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The short answer: HRT and Retatrutide are generally complementary

FFA3 is expressed in the enteric sympathetic ganglion (Nhr et al., 2015) and the GLP-1R is expressed in vagal afferent neurons including the nodose ganglion (Zhang et al., 2020), suggesting the possibility of functional interactions between these two receptors at these neuronal locations

Animal data covers relatively short treatment cycles, and extrapolating beyond that requires clinical judgment