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Patients should seek urgent medical advice if they experience any of the following after taking any weight loss supplement or medicine: Call 999 immediately for severe chest pain, difficulty breathing, or signs of a serious allergic reaction (anaphylaxis) such as swelling of the face, lips, or throat Contact your GP or call NHS 111 for severe or persistent abdominal pain, palpitations, significant changes in mood or behaviour, or a skin rash The MHRA operates a Yellow Card reporting scheme for suspected adverse reactions to both medicines and supplements