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10.1038/srep16205 Sci

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2021 Dec 1 [cited 2023 May 29];21(1)

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ATM-deficient mice, worms, and cell models demonstrated accumulation of cytoplasmic DNA, hyperactivation of PARP1, and low NAD + levels 111,288

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The fact that tirzepatide at therapeutic doses did not push calcitonin into concerning ranges provides direct biochemical evidence against the rodent-to-human translation of C-cell risk

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