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GLP-1 drugs act much more slowly, with the goal of a more permanent result

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"GLP-1 receptor agonists in MASH: mechanisms and clinical evidence." Alimentary Pharmacology & Therapeutics

Other serious but rare side effects include pancreatitis (severe stomach pain, fever, nausea, vomiting), gallbladder problems (yellowing of skin or eyes, upper stomach pain), kidney injury (decreased urination, swelling), diabetic retinopathy (vision changes), severe allergic reactions (rash, swelling of face/throat, difficulty breathing), increased heart rate, and new or worsening depression or suicidal thoughts