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Although the GLP-1R agonists are used to treat type 2 diabetes in clinic (52, 53), there are direct evidences about the therapeutic actions of GLP-1-based therapies in different healthy conditions in humans, including adipogenesis, osteogenesis, and nociception, with many signaling pathways are involved (54)
Visceral fat is metabolically active in ways that promote inflammation and insulin resistance, both of which have downstream effects on hormonal balance
GLP-1 weight-loss drugs may lower the need for knee replacement News briefs Reviewed by Robert H
Hypoxia, acidification and oxidative stress in cells cultured at large distances from an oxygen source
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