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Animal data show enhanced metabolic adaptation when MOTS-c is dosed before exercise
Stevenson LW, Bellil D, Grover-Mckay M et al (1987) Effects of afterload reduction (diuretics and vasodilators) on left ventricular volume and mitral regurgitation in severe congestive heart failure secondary to ischemic or idiopathic dilated cardiomyopathy
The practical takeaway is that both genders respond strongly, with women showing a modest advantage in absolute weight loss percentage
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