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Furin impacts the cellular entry of SARS-CoV-2 in a unique manner by pre-activation of S2 subunit thereby reducing viral dependance on other human proteases for cellular entry 54

Additionally, HGF displays pleiotropic functions in a variety of tissues and organs and therapeutic applications of investigational HGF drugs (application of new drugs developed on the basis of these HGF-mediated effects, for clinical therapy) have been tested in various diseases as described before

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