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Consequently, only 1015% of GLP-1 reaches circulation intact, leading to fasting plasma levels of only 015 pmol/L

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First, we revealed that pre-infusion CAR T cell products from LTR have an altered immunometabolic signature acquiring features of memory T cells, which is associated with improved anti-tumor efficacy and persistence, including increased OXPHOS, markers of fatty acid oxidation, and PPP activities (Fig