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examined the effect of liraglutide on NAFLD in a high-fat diet (HFD) SpragueDawley (SD) rat model for 4 weeks and reported improvement in hepatic steatosis, lobular inflammation, and ballooning
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Yet a large group of patients still had classic IBS symptoms plus brain fog and negative SIBO breath tests
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In the head-to-head SURMOUNT-5 trial (NEJM, 2025), Mounjaro produced 20.2% average weight loss vs 13.7% for Wegovy over 72 weeks
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