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Confirmed in isolated aortic tissue (Hsieh et al., 2020)
The primary routes of human exposure include: Contaminated food: Grains, corn, nuts (especially peanuts, pistachios, and cashews), coffee beans, dried fruits, and spices are the most common dietary sources
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In patients, activation of the NRF2 pathway is associated with more aggressive disease (Homma et al, 2009
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