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Oxidation of alpha-ketoglutarate is required for reductive carboxylation in cancer cells with mitochondrial defects

A formula listed with an asterisk * indicates that this is available per the discretion of our Nurse Practitioners who are looking at whether you have any risk factors that would make this not the best idea at this time (ex: pregnant, nursing, or have certain kidney or cardiac disorders.) Vitamin injections can help to support your overall health and wellness journey

Vitamin B12 deficiency can also result from poor nutrition, cancer, HIV, during pregnancy, old age, due to alcoholism

Cell Death & Disease, 11 (5), 312