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Mice with this condition were supplemented with UroA, which led to decreased fasting blood glucose, glycated haemoglobin levels, plasma C-peptide, malondialdehyde (MDA) and interleukin-1 levels

Moving forward, the most realistic near-term translational path lies in combining relatively simple, biocompatible bone-targeted nanocarriers (such as alendronate-functionalized liposomal or polymeric systems) to specifically co-deliver immunogenic cell death (ICD)-inducing standard chemotherapeutics alongside established immune checkpoint inhibitors (e.g., anti-PD-1/PD-L1) or myeloid cell modulators

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sgRNA Scorer 2.0: a species-independent model to predict CRISPR/Cas9 activity